HLA-Associated Viral Mutations Are Common in Human Immunodeficiency Virus Type 1 Elite Controllers

Elite controllers (EC) of human immunodeficiency virus type 1 (HIV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8(+) T lymphocytes are believed to play a crucial role in viral containment, but the degree of immune imprinting and compen...

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Detalhes bibliográficos
Main Authors: Miura, Toshiyuki, Brumme, Chanson J., Brockman, Mark A., Brumme, Zabrina L., Pereyra, Florencia, Block, Brian L., Trocha, Alicja, John, Mina, Mallal, Simon, Harrigan, P. Richard, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655568/
https://ncbi.nlm.nih.gov/pubmed/19153230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02459-08
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