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Absence of CD4(+) T Lymphocytes, CD8(+) T Lymphocytes, or B Lymphocytes Has Different Effects on the Efficacy of Posaconazole and Benznidazole in Treatment of Experimental Acute Trypanosoma cruzi Infection

We investigated the influence of CD4(+) T lymphocytes, CD8(+) T lymphocytes, and B lymphocytes on the efficacy of posaconazole (POS) and the reference drug benznidazole (BZ) during treatment of acute Trypanosoma cruzi infection in a murine model. Wild-type mice infected with T. cruzi and treated wit...

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Autors principals: Ferraz, Marcela L., Gazzinelli, Ricardo T., Alves, Rosana O., Urbina, Julio A., Romanha, Alvaro J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612170/
https://ncbi.nlm.nih.gov/pubmed/19001113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00779-08
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