Interleukin-12 Enhances In Vivo Parasiticidal Effect of Benznidazole during Acute Experimental Infection with a Naturally Drug-Resistant Strain of Trypanosoma cruzi

The roles of gamma interferon (IFN-γ) and interleukin-12 (IL-12) in mediating and/or enhancing the in vivo trypanosomicidal activity of the nitroheterocyclic derivative benznidazole (Bz) were evaluated during early stages of experimental Chagas’ disease. Our results show that treatment of Trypanosom...

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Main Authors: Michailowsky, Vladimir, Murta, Silvane M. F., Carvalho-Oliveira, Leonardo, Pereira, Maria E. S., Ferreira, Ludmila R. P., Brener, Zigman, Romanha, Alvaro J., Gazzinelli, Ricardo T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 1998
Ábhair:
Experimental Therapeutics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC105888/
https://ncbi.nlm.nih.gov/pubmed/9756754
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