INHIBITION OF HUMAN ACETYL- AND BUTYRYLCHOLINESTERASE BY NOVEL CARBAMATES OF (−)- AND (+)-TETRAHYDROFUROBENZOFURAN AND METHANOBENZODIOXEPINE

A new enantiomeric synthesis utilizing classical resolution provided two novel series of optically active inhibitors of cholinesterase: (−)- and (+)- O-carbamoyl phenols of tetrahydrofurobenzofuran and methanobenzodioxepine. An additional two series of (−)- and (+)-O-carbamoyl phenols of pyrroloindo...

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Bibliographische Detailangaben
Hauptverfasser: Luo, Weiming, Yu, Qian-sheng, Kulkarni, Santosh S., Parrish, Damon A., Holloway, Harold W., Tweedie, David, Shafferman, Avigdor, Lahiri, Debomoy K., Brossi, Arnold, Greig, Nigel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610450/
https://ncbi.nlm.nih.gov/pubmed/16570913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm050578p
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