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Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors
2-Thioribothymidine (s(2)T), a modified uridine, is found at position 54 in transfer RNAs (tRNAs) from several thermophiles; s(2)T stabilizes the L-shaped structure of tRNA and is essential for growth at higher temperatures. Here, we identified an ATPase (tRNA-two-thiouridine C, TtuC) required for t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2609741/ https://ncbi.nlm.nih.gov/pubmed/19037260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.246 |
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