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Dual Role of the Molybdenum Cofactor Biosynthesis Protein MOCS3 in tRNA Thiolation and Molybdenum Cofactor Biosynthesis in Humans

We studied two pathways that involve the transfer of persulfide sulfur in humans, molybdenum cofactor biosynthesis and tRNA thiolation. Investigations using human cells showed that the two-domain protein MOCS3 is shared between both pathways. MOCS3 has an N-terminal adenylation domain and a C-termin...

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Autors principals: Chowdhury, Mita Mullick, Dosche, Carsten, Löhmannsröben, Hans-Gerd, Leimkühler, Silke
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366815/
https://ncbi.nlm.nih.gov/pubmed/22453920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351429
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