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Dual Role of the Molybdenum Cofactor Biosynthesis Protein MOCS3 in tRNA Thiolation and Molybdenum Cofactor Biosynthesis in Humans

We studied two pathways that involve the transfer of persulfide sulfur in humans, molybdenum cofactor biosynthesis and tRNA thiolation. Investigations using human cells showed that the two-domain protein MOCS3 is shared between both pathways. MOCS3 has an N-terminal adenylation domain and a C-termin...

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Bibliografische gegevens
Hoofdauteurs: Chowdhury, Mita Mullick, Dosche, Carsten, Löhmannsröben, Hans-Gerd, Leimkühler, Silke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366815/
https://ncbi.nlm.nih.gov/pubmed/22453920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351429
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