Protection of mice against lethal endotoxemia by a lipid A precursor.
Lipid X, the major biosynthetic precursor of lipid A, has recently been described. Although lipid X is a mitogen and coagulates the Limulus amebocyte lysate, we found that it is not lethal for mice, even when given in large doses (2 X 10(6) micrograms/kg). Furthermore, lipid X was found to give part...
Shranjeno v:
| izdano v: | Infect Immun |
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| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1986
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3519466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.52.3.905-907.1986 |
| Oznake: |
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