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Protection of mice against lethal endotoxemia by a lipid A precursor.

Lipid X, the major biosynthetic precursor of lipid A, has recently been described. Although lipid X is a mitogen and coagulates the Limulus amebocyte lysate, we found that it is not lethal for mice, even when given in large doses (2 X 10(6) micrograms/kg). Furthermore, lipid X was found to give part...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Proctor, R A, Will, J A, Burhop, K E, Raetz, C R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3519466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.52.3.905-907.1986
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