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Protection of mice against lethal endotoxemia by a lipid A precursor.

Lipid X, the major biosynthetic precursor of lipid A, has recently been described. Although lipid X is a mitogen and coagulates the Limulus amebocyte lysate, we found that it is not lethal for mice, even when given in large doses (2 X 10(6) micrograms/kg). Furthermore, lipid X was found to give part...

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Main Authors: Proctor, R A, Will, J A, Burhop, K E, Raetz, C R
Format: Artigo
Jezik:Inglês
Izdano: 1986
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC260947/
https://ncbi.nlm.nih.gov/pubmed/3519466
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