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Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller
Telomeres recruit telomerase and differentiate chromosome ends from sites of DNA damage. Although the DNA damage checkpoint PI3-kinases ATM and ATR localize to telomeres and promote telomerase activation, activation of their downstream checkpoint pathway targets is inhibited. Here, we show that the...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2607071/ https://ncbi.nlm.nih.gov/pubmed/19141478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.498608 |
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