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Tpz1-Ccq1 and Tpz1-Poz1 Interactions within Fission Yeast Shelterin Modulate Ccq1 Thr93 Phosphorylation and Telomerase Recruitment

In both fission yeast and humans, the shelterin complex plays central roles in regulation of telomerase recruitment, protection of telomeres against DNA damage response factors, and formation of heterochromatin at telomeres. While shelterin is essential for limiting activation of the DNA damage chec...

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Autors principals: Harland, Jennifer L., Chang, Ya-Ting, Moser, Bettina A., Nakamura, Toru M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199508/
https://ncbi.nlm.nih.gov/pubmed/25330395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004708
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