Nalaganje...

Iodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis Inhibitors

The thyroid hormone and retinol transporter protein known as transthyretin (TTR) is in the origin of one of the 20 or so known amyloid diseases. TTR self assembles as a homotetramer leaving a central hydrophobic channel with two symmetrical binding sites. The aggregation pathway of TTR into amiloid...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Mairal, Teresa, Nieto, Joan, Pinto, Marta, Almeida, Maria Rosário, Gales, Luis, Ballesteros, Alfredo, Barluenga, José, Pérez, Juan J., Vázquez, Jesús T., Centeno, Nuria B., Saraiva, Maria Joao, Damas, Ana M., Planas, Antoni, Arsequell, Gemma, Valencia, Gregorio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607018/
https://ncbi.nlm.nih.gov/pubmed/19125186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004124
Oznake: Označite
Brez oznak, prvi označite!