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Site Selectivity of Competitive Antagonists for the Mouse Adult Muscle Nicotinic Acetylcholine Receptor

The muscle-type nicotinic acetylcholine receptor has two nonidentical binding sites for ligands. The selectivity of acetylcholine and the competitive antagonists (+)-tubocurarine and metocurine for adult mouse receptors is known. Here, we examine the site selectivity for four other competitive antag...

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Bibliographic Details
Main Authors: Liu, Man, Dilger, James P.
Format: Artigo
Language:Inglês
Published: American Society for Pharmacology and Experimental Therapeutics 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606922/
https://ncbi.nlm.nih.gov/pubmed/18842832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051060
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