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The kinetics of competitive antagonism of nicotinic acetylcholine receptors at physiological temperature

Detailed information about the ligand-binding site of nicotinic acetylcholine receptors has emerged from structural and mutagenesis experiments. However, these approaches provide only static images of ligand–receptor interactions. Kinetic measurements of changes in protein function are needed to dev...

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Autors principals: Demazumder, Deeptankar, Dilger, James P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375649/
https://ncbi.nlm.nih.gov/pubmed/18063662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.143289
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