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The kinetics of competitive antagonism of nicotinic acetylcholine receptors at physiological temperature
Detailed information about the ligand-binding site of nicotinic acetylcholine receptors has emerged from structural and mutagenesis experiments. However, these approaches provide only static images of ligand–receptor interactions. Kinetic measurements of changes in protein function are needed to dev...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375649/ https://ncbi.nlm.nih.gov/pubmed/18063662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.143289 |
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