Characterization of murine monoclonal antibodies that recognize neutralizing epitopes on human C5a.

We generated a panel of 10 murine monoclonal antibodies (MAbs) that recognize human complement fragment C5a. These MAbs were characterized for their ability to immunoprecipitate 125I-labeled C5a, bind C5a in solid-phase enzyme immunoassay, and block 125I-labeled C5a binding to polymorphonuclear leuk...

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Bibliographic Details
Main Authors: Larrick, J W, Wang, J, Fendly, B M, Chenoweth, D E, Kunkel, S L, Deinhart, T
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC260616/
https://ncbi.nlm.nih.gov/pubmed/2440808
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