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Oncogenic Activation of MAP Kinase by BRAF Pseudogene in Thyroid Tumors

Activating BRAF mutations have been reported in 40% of papillary thyroid carcinomas (PTCs). The involvement of BRAF pseudogene in thyroid tumorigenesis has not previously been studied. We investigated BRAF pseudogene expression in 68 thyroid tumors: 16 multinodular goiters, 43 classic PTCs, 6 follic...

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Hlavní autoři: Zou, Minjing, Baitei, Essa Y, Alzahrani, Ali S, Al-Mohanna, Futwan, Farid, Nadir R, Meyer, Brian, Shi, Yufei
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606119/
https://ncbi.nlm.nih.gov/pubmed/19107232
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