RET/PTC1-Driven Neoplastic Transformation and Proinvasive Phenotype of Human Thyrocytes Involve Met Induction and β-Catenin Nuclear Translocation

Activation of the RET gene by chromosomal rearrangements generating RET/PTC oncogenes is a frequent, early, and causative event in papillary thyroid carcinoma (PTC). We have previously shown that, in human primary thyrocytes, RET/PTC1 induces a transcriptional program including the MET proto-oncogen...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Cassinelli, Giuliana, Favini, Enrica, Degl'Innocenti, Debora, Salvi, Alessandro, De Petro, Giuseppina, Pierotti, Marco A, Zunino, Franco, Borrello, Maria Grazia, Lanzi, Cinzia
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606114/
https://ncbi.nlm.nih.gov/pubmed/19107227
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares