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Heparan Sulfate Mimetics in Cancer Therapy: The Challenge to Define Structural Determinants and the Relevance of Targets for Optimal Activity

Beyond anticoagulation, the therapeutic potential of heparin derivatives and heparan sulfate (HS) mimetics (functionally defined HS mimetics) in oncology is related to their ability to bind and modulate the function of a vast array of HS-binding proteins with pivotal roles in cancer growth and progr...

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Bibliographic Details
Published in:Molecules
Main Authors: Lanzi, Cinzia, Cassinelli, Giuliana
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278363/
https://ncbi.nlm.nih.gov/pubmed/30413079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112915
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