Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene

Rearrangements of the RET receptor tyrosine kinase gene generating RET/PTC oncogenes are specific to papillary thyroid carcinoma (PTC), the most frequent thyroid tumor. Here, we show that the RET/PTC1 oncogene, when exogenously expressed in primary normal human thyrocytes, induces the expression of...

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Detalhes bibliográficos
Main Authors: Borrello, Maria Grazia, Alberti, Luisella, Fischer, Andrew, Degl'Innocenti, Debora, Ferrario, Cristina, Gariboldi, Manuela, Marchesi, Federica, Allavena, Paola, Greco, Angela, Collini, Paola, Pilotti, Silvana, Cassinelli, Giuliana, Bressan, Paola, Fugazzola, Laura, Mantovani, Alberto, Pierotti, Marco A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253545/
https://ncbi.nlm.nih.gov/pubmed/16203990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503039102
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