Nematode Homologue of PQBP1, a Mental Retardation Causative Gene, Is Involved in Lipid Metabolism

BACKGROUND: PQBP1 is a causative gene for X-linked mental retardation (MR) whose patients frequently show lean body. C. elegans has a strictly conserved homologue gene of PQBP1, T21D12.3. METHODOLOGY AND PRINCIPAL FINDINGS: We generated Venus-transgenic and T21D12.3-mutant nematodes to analyze devel...

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Autores principales: Takahashi, Keiko, Yoshina, Sawako, Masashi, Maekawa, Ito, Wakana, Inoue, Takao, Shiwaku, Hiroki, Arai, Hiroyuki, Mitani, Shohei, Okazawa, Hitoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606030/
https://ncbi.nlm.nih.gov/pubmed/19119319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004104
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