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FTDP-17 Mutations in Tau Alter the Regulation of Microtubule Dynamics: AN “ALTERNATIVE CORE” MODEL FOR NORMAL AND PATHOLOGICAL TAU ACTION
Mutations affecting either the structure or regulation of the microtubule-associated protein Tau cause neuronal cell death and dementia. However, the molecular mechanisms mediating these deleterious effects remain unclear. Among the most characterized activities of Tau is the ability to regulate mic...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606000/ https://ncbi.nlm.nih.gov/pubmed/18940799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803519200 |
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