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HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase

Human T-cell leukemia virus type-1 is the causative agent for adult T-cell leukemia. Previous research has established that the viral oncoprotein Tax mediates the transformation process by impairing cell cycle control and cellular response to DNA damage. We showed previously that Tax sequesters huCh...

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Autors principals: Durkin, Sarah S., Guo, Xin, Fryrear, Kimberly A., Mihaylova, Valia T., Gupta, Saurabh K., Belgnaoui, S. Mehdi, Haoudi, Abdelali, Kupfer, Gary M., Semmes, O. John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605996/
https://ncbi.nlm.nih.gov/pubmed/18957425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804931200
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