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Human T-Cell Leukemia Virus I Tax Protein Sensitizes p53-Mutant Cells to DNA Damage

Mutations in p53 are a common cause of resistance of cancers to standard chemotherapy and, thus, treatment failure. Reports have shown that Tax, a human T-cell leukemia virus type I encoded protein that has been associated with genomic instability and perturbation of transcription and cell cycle, se...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Mihaylova, Valia T., Green, Allison M., Khurgel, Moshe, Semmes, Oliver J., Kupfer, Gary M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939382/
https://ncbi.nlm.nih.gov/pubmed/18559532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5070
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