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Native R-loops Persist throughout the Mouse Mitochondrial DNA Genome
Mammalian mtDNA has been found here to harbor RNA-DNA hybrids at a variety of locations throughout the genome. The R-loop, previously characterized in vitro at the leading strand replication origin (O(H)), is isolated as a native RNA-DNA hybrid copurifying with mtDNA. Surprisingly, other mitochondri...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605977/ https://ncbi.nlm.nih.gov/pubmed/18986989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806174200 |
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