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Pirt, a Phosphoinositide-Binding Protein, Functions as a Regulatory Subunit of TRPV1
SUMMARY: Transient receptor potential vanilloid 1 (TRPV1) is a molecular sensor of noxious heat and capsaicin. Its channel activity can be modulated by several mechanisms. Here we identify a membrane protein, Pirt, as a regulator of TRPV1. Pirt is expressed in most nociceptive neurons in the dorsal...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605970/ https://ncbi.nlm.nih.gov/pubmed/18455988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.02.053 |
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