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Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch

Itch, or pruritus, is an important clinical problem whose molecular basis has yet to be understood. Recent work has begun to identify genes that contribute to detecting itch at the molecular level. Here we show that Pirt, known to play a vital part in sensing pain through modulation of the transient...

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Detalhes bibliográficos
Principais autores: Patel, Kush N., Liu, Qin, Meeker, Sonya, Undem, Bradley J., Dong, Xinzhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105090/
https://ncbi.nlm.nih.gov/pubmed/21655234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020559
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