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Signal transduction activator of transcription 5 (STAT5) dysfunction in autoimmune monocytes and macrophages
Autocrine granulocyte macrophage-colony stimulating factor (GM-CSF) sequentially activates intracellular components in monocyte/macrophage production of the pro-inflammatory and immunoregulatory prostanoid, prostaglandin E2 (PGE2). GM-CSF first induces STAT5 signaling protein phosphorylation, then p...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605968/ https://ncbi.nlm.nih.gov/pubmed/15927792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2005.02.001 |
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