GM-CSF Induces STAT5 Binding at Epigenetic Regulatory Sites within the Csf2 Promoter of Nonobese Diabetic (NOD) Mouse Myeloid Cells

Myeloid cells from nonobese diabetic (NOD) mouse and human type 1 diabetic (T1D) patients overexpress granulocyte-macrophage colony stimulation factor (GM-CSF). This overproduction prolongs the activation of signal transduction and activator of transcription 5 (STAT5) proteins, involved in GM-CSF-in...

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Hlavní autoři: Seydel, F., Garrigan, E., Stutevoss, B., Belkin, N., Makadia, B., Carter, J., Shi, J.-D., Davoodi-Semiromi, A., McDuffie, M., Litherland, S. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744087/
https://ncbi.nlm.nih.gov/pubmed/18945591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2008.08.010
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