Overexpression of OATP1B3 confers apoptotic resistance in colon cancer

Organic anion transporting polypeptide 1B3 (OATP1B3, SLCO1B3) is normally expressed in hepatocytes. In this study, we demonstrated frequent overexpression of OATP1B3 in colorectal adenocarcinomas. Quantitative RT-PCR analysis of 17 colon tumors indicated tumoral overexpression of OATP1B3 by ~100 fol...

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Detalhes bibliográficos
Main Authors: Lee, Wooin, Belkhiri, Abbes, Lockhart, A. Craig, Merchant, Nipun, Glaeser, Hartmut, Harris, Elizabeth I., Washington, M. Kay, Brunt, Elizabeth M., Zaika, Alex, Kim, Richard B., El-Rifai, Wael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605661/
https://ncbi.nlm.nih.gov/pubmed/19074900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1984
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