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Antidepressants of the Serotonin-Antagonist Type Increase Body Fat and Decrease Lifespan of Adult Caenorhabditis elegans

It was recently suggested that specific antidepressants of the serotonin-antagonist type, namely mianserin and methiothepin, may exert anti-aging properties and specifically extend lifespan of the nematode C.elegans by causing a state of perceived calorie restriction (Petrascheck M, Ye X, Buck LB: A...

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Bibliographic Details
Main Authors: Zarse, Kim, Ristow, Michael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605556/
https://ncbi.nlm.nih.gov/pubmed/19112515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004062
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