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Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKα-dependent cyclin D1 down-regulation

It is well-known that insoluble nickel compounds possess much more potent carcinogenic activities as compared with soluble nickel compounds. Although it is assumed that the different entry and clearance rate are responsible for the difference, the mechanisms underlying the different carcinogenic act...

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Detalhes bibliográficos
Main Authors: Ouyang, Weiming, Zhang, Dongyun, Li, Jingxia, Verma, Udit N., Costa, Max, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605425/
https://ncbi.nlm.nih.gov/pubmed/18792914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21590
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