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Preparation of Nanocrystals for Insoluble Drugs by Top-Down Nanotechnology with Improved Solubility and Bioavailability

Midazolam is a rapidly effective benzodiazepine drug that is widely used as a sedative worldwide. Due to its poor solubility in a neutral aqueous solution, the clinical use of midazolam is significantly limited. As one of the most promising formulations for poorly water-soluble drugs, nanocrystals h...

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Foilsithe in:Molecules
Main Authors: Zhang, Xun, Li, Zhiguo, Gao, Jing, Wang, Zengming, Gao, Xiang, Liu, Nan, Li, Meng, Zhang, Hui, Zheng, Aiping
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179175/
https://ncbi.nlm.nih.gov/pubmed/32121076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25051080
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