N-Arachidonyl Maleimide Potentiates the Pharmacological and Biochemical Effects of the Endocannabinoid 2-Arachidonylglycerol through Inhibition of Monoacylglycerol Lipase

Inhibition of the metabolism of the endocannabinoids, anandamide (AEA) and 2-arachidonyl glycerol (2-AG), by their primary metabolic enzymes, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively, has the potential to increase understanding of the physiological functions...

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Autores principales: Burston, James J., Sim-Selley, Laura J., Harloe, John P., Mahadevan, Anu, Razdan, Raj K., Selley, Dana E., Wiley, Jenny L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605346/
https://ncbi.nlm.nih.gov/pubmed/18682568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.141382
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