Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus

Although the importance of cytotoxic T lymphocytes and neutralizing antibodies for antiviral defense is well known, the antiviral mechanism of Th1 remains unclear. We show that Th1 cells mediate noncytolytic antiviral protection independent of direct lysis through local secretion of IFN-γ after herp...

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Bibliographic Details
Main Authors: Iijima, Norifumi, Linehan, Melissa M., Zamora, Melodie, Butkus, Debbie, Dunn, Robert, Kehry, Marilyn R., Laufer, Terri M., Iwasaki, Akiko
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605233/
https://ncbi.nlm.nih.gov/pubmed/19047439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082039
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