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A neuron-specific role for autophagy in antiviral defense against herpes simplex virus

Type I interferons (IFNs) are considered to be the universal mechanism by which viral infections are controlled. However, many IFN-stimulated genes (ISGs) rely on antiviral pathways that are toxic to host cells, which may be detrimental in non-renewable cell types, such as neurons. We show that dors...

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Autors principals: Yordy, Brian, Iijima, Norifumi, Huttner, Anita, Leib, David, Iwasaki, Akiko
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454454/
https://ncbi.nlm.nih.gov/pubmed/22980330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.07.013
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