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A neuron-specific role for autophagy in antiviral defense against herpes simplex virus
Type I interferons (IFNs) are considered to be the universal mechanism by which viral infections are controlled. However, many IFN-stimulated genes (ISGs) rely on antiviral pathways that are toxic to host cells, which may be detrimental in non-renewable cell types, such as neurons. We show that dors...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3454454/ https://ncbi.nlm.nih.gov/pubmed/22980330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.07.013 |
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