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Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2

Herpes simplex virus (HSV) type 2 infection occurs primarily at the genital mucosal surfaces and is a leading cause of ulcerative lesions. Despite the availability of animal models for HSV-2 infection, little is known regarding the mechanism of immune induction within the vaginal mucosa. Here, we ex...

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Bibliografske podrobnosti
Main Authors: Zhao, Xinyan, Deak, Eszter, Soderberg, Kelly, Linehan, Melissa, Spezzano, David, Zhu, Jia, Knipe, David M., Iwasaki, Akiko
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193810/
https://ncbi.nlm.nih.gov/pubmed/12538655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021109
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