4-Aminobiphenyl Downregulation of NAT2 Acetylator Genotype–Dependent N- and O-acetylation of Aromatic and Heterocyclic Amine Carcinogens in Primary Mammary Epithelial Cell Cultures from Rapid and Slow Acetylator Rats

Aromatic and heterocyclic amine carcinogens present in the diet and in cigarette smoke induce breast tumors in rats. N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2) enzymes have important roles in their metabolic activation and deactivation. Human epidemiological studies suggest that g...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jefferson, Felicia A., Xiao, Gong H., Hein, David W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Systems Toxicology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605175/
https://ncbi.nlm.nih.gov/pubmed/18842621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn216
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