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Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21(WAF1/CIP1) dependent

OSU03012 is a non-COX inhibiting celecoxib derivative with growth inhibiting and apoptotic activity in many cancer cell lines. To investigate mechanisms related to cell cycle proteins in growth inhibition and apoptosis induced by OSU03012, the primary human oral epithelial cell line, TE1177, was tra...

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Detalhes bibliográficos
Main Authors: Ding, Haiming, Han, Chunhua, Guo, Dongmei, Wang, Dasheng, Duan, Wenrui, Chen, Ching-Shih, D'Ambrosio, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605165/
https://ncbi.nlm.nih.gov/pubmed/18798266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23895
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