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Structure of membrane-bound α-synuclein from site-directed spin labeling and computational refinement

α-Synuclein is known to play a causative role in Parkinson disease. Although its physiological functions are not fully understood, α-synuclein has been shown to interact with synaptic vesicles and modulate neurotransmitter release. However, the structure of its physiologically relevant membrane-boun...

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Detalhes bibliográficos
Main Authors: Jao, Christine C., Hegde, Balachandra G., Chen, Jeannie, Haworth, Ian S., Langen, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605001/
https://ncbi.nlm.nih.gov/pubmed/19066219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807826105
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