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Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy

Oxygen-induced retinopathy (OIR) in the mouse, like the analogous human disease retinopathy of prematurity, is an ischemic retinopathy dependent on oxygen-induced vascular obliteration. We tested the hypothesis that chemically overriding the oxygen-induced downregulation of hypoxia-inducible factor...

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Bibliografische gegevens
Hoofdauteurs: Sears, Jonathan E., Hoppe, George, Ebrahem, Quteba, Anand-Apte, Bela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604934/
https://ncbi.nlm.nih.gov/pubmed/19057008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805817105
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