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Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy
Oxygen-induced retinopathy (OIR) in the mouse, like the analogous human disease retinopathy of prematurity, is an ischemic retinopathy dependent on oxygen-induced vascular obliteration. We tested the hypothesis that chemically overriding the oxygen-induced downregulation of hypoxia-inducible factor...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
National Academy of Sciences
2008
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604934/ https://ncbi.nlm.nih.gov/pubmed/19057008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805817105 |
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