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Electron tomography of early melanosomes: Implications for melanogenesis and the generation of fibrillar amyloid sheets

Melanosomes are lysosome-related organelles (LROs) in which melanins are synthesized and stored. Early stage melanosomes are characterized morphologically by intralumenal fibrils upon which melanins are deposited in later stages. The integral membrane protein Pmel17 is a component of the fibrils, ca...

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Библиографические подробности
Главные авторы: Hurbain, Ilse, Geerts, Willie J. C., Boudier, Thomas, Marco, Sergio, Verkleij, Arie J., Marks, Michael S., Raposo, Graç
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604932/
https://ncbi.nlm.nih.gov/pubmed/19033461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803488105
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