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Electron tomography of early melanosomes: Implications for melanogenesis and the generation of fibrillar amyloid sheets

Melanosomes are lysosome-related organelles (LROs) in which melanins are synthesized and stored. Early stage melanosomes are characterized morphologically by intralumenal fibrils upon which melanins are deposited in later stages. The integral membrane protein Pmel17 is a component of the fibrils, ca...

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Bibliografiske detaljer
Main Authors: Hurbain, Ilse, Geerts, Willie J. C., Boudier, Thomas, Marco, Sergio, Verkleij, Arie J., Marks, Michael S., Raposo, Graç
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604932/
https://ncbi.nlm.nih.gov/pubmed/19033461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803488105
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