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Electron tomography of early melanosomes: Implications for melanogenesis and the generation of fibrillar amyloid sheets
Melanosomes are lysosome-related organelles (LROs) in which melanins are synthesized and stored. Early stage melanosomes are characterized morphologically by intralumenal fibrils upon which melanins are deposited in later stages. The integral membrane protein Pmel17 is a component of the fibrils, ca...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604932/ https://ncbi.nlm.nih.gov/pubmed/19033461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803488105 |
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