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Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL
B cell chronic lymphocytic leukemia (B-CLL) is the most common human leukemia. Deregulation of the T cell leukemia/lymphoma 1 (TCL1) oncogene in mouse B cells causes a CD5-positive leukemia similar to aggressive human B-CLLs. To examine the mechanisms by which Tcl1 protein exerts oncogenic activity...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604915/ https://ncbi.nlm.nih.gov/pubmed/19064921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810965105 |
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