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Comparing Platforms for C. elegans Mutant Identification Using High-Throughput Whole-Genome Sequencing

BACKGROUND: Whole-genome sequencing represents a promising approach to pinpoint chemically induced mutations in genetic model organisms, thereby short-cutting time-consuming genetic mapping efforts. PRINCIPAL FINDINGS: We compare here the ability of two leading high-throughput platforms for paired-e...

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Main Authors: Shen, Yufeng, Sarin, Sumeet, Liu, Ye, Hobert, Oliver, Pe'er, Itsik
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603312/
https://ncbi.nlm.nih.gov/pubmed/19107202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004012
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