HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion

The cancer stem cell hypothesis proposes that cancers arise in stem/progenitor cells through disregulation of self-renewal pathways generating tumors which are driven by a component of “tumor initiating cells” retaining stem cells properties. The HER2 gene is amplified in 20–30% of human breast canc...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Korkaya, Hasan, Paulson, Amanda, Iovino, Flora, Wicha, Max S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602947/
https://ncbi.nlm.nih.gov/pubmed/18591932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.207
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