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HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
The cancer stem cell hypothesis proposes that cancers arise in stem/progenitor cells through disregulation of self-renewal pathways generating tumors which are driven by a component of “tumor initiating cells” retaining stem cells properties. The HER2 gene is amplified in 20–30% of human breast canc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602947/ https://ncbi.nlm.nih.gov/pubmed/18591932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.207 |
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