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Caspase-mediated Bak Activation and Cytochrome c Release during Intrinsic Apoptotic Cell Death in Jurkat Cells

Mitochondrial outer membrane permeabilization and the release of intermembrane space proteins, such as cytochrome c, are early events during intrinsic (mitochondria-mediated) apoptotic signaling. Although this process is generally accepted to require the activation of Bak or Bax, the underlying mech...

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Detalhes bibliográficos
Main Authors: Shawgo, Mary E., Shelton, Shary N., Robertson, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602908/
https://ncbi.nlm.nih.gov/pubmed/18927073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807656200
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