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Focal Adhesion Kinase as a RhoA-activable Signaling Scaffold Mediating Akt Activation and Cardiomyocyte Protection

RhoA a small G-protein that has an established role in cell growth and in regulation of the actin cytoskeleton. Far less is known about whether RhoA can modulate cell fate. We previously reported that sustained RhoA activation induces cardiomyocyte apoptosis (Del Re, D. P., Miyamoto, S., and Brown,...

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Détails bibliographiques
Auteurs principaux: Del Re, Dominic P., Miyamoto, Shigeki, Brown, Joan Heller
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602897/
https://ncbi.nlm.nih.gov/pubmed/18854312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804036200
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