Properties of pseudo-complementary DNA substituted with weakly pairing analogs of guanine or cytosine

A straightforward enzymatic protocol for converting regular DNA into pseudo-complementary DNA could improve the performance of oligonucleotide microarrays by generating readily hybridizable structure-free targets. Here we screened several highly destabilizing analogs of G and C for one that could be...

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Bibliografske podrobnosti
Main Authors: Lahoud, Georges, Timoshchuk, Victor, Lebedev, Alexandre, Arar, Khalil, Hou, Ya-Ming, Gamper, Howard
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Chemistry and Synthetic Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602760/
https://ncbi.nlm.nih.gov/pubmed/18987000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn797
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