Enzymatic synthesis of structure-free DNA with pseudo-complementary properties

Long single-stranded DNAs and RNAs possess considerable secondary structure under conditions that support stable hybrid formation with oligonucleotides. Consequently, different oligomeric probes can hybridize to the same target with efficiencies that vary by several orders of magnitude. The ability...

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Detalhes bibliográficos
Main Authors: Lahoud, Georges, Timoshchuk, Victor, Lebedev, Alexandre, de Vega, Miguel, Salas, Margarita, Arar, Khalil, Hou, Ya-Ming, Gamper, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2425472/
https://ncbi.nlm.nih.gov/pubmed/18448471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn209
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